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The most common side effect is and dyspepsia, occurring in up to 30% of patients.

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Coronary risk assessment among intermediate risk patients using a clinical and biomarker based algorithm developed and validated in two population cohorts.

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Glucagon-like peptide 1 (GLP-1) analogues are the foundation of incretin-based therapies which are to target this previously unrecognized feature of DM pathophysiology resulting in sustained improvements in glycemic control and improved body weight control.

Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics.

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Glimepiride, a long-acting sulfonylurea, may partly fulfil this role as it has a lower affinity for the β-cell receptor than glyburide (), and its insulin secretory capacity is lower in both the fasting () and postprandial () states.

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Luyckx FH, Desaive C, Thiry A, Dewe W, Scheen AJ, Gielen JE, Lefebvre PJ: Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty.

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Therefore, while “aspirin resistance” appears higher in the diabetic patients when measured by a variety of ex vivo and in vitro methods (platelet aggrenometry, measurement of thromboxane B 2), these observations alone are insufficient to empirically recommend higher doses of aspirin be used in the diabetic patient at this time.

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After single and multiple oral doses in healthy subjects or in patients with type 2 diabetes, peak plasma drug levels (C max) occur within 1 hour (T max).

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